Prescription Drug Coverage

Spironolactone (Aldactone) Medicare Coverage

You may be able to find Medicare plan options in your area that cover Spironolactone or Aldactone. Learn more about Spironolactone and find Medicare Advantage plans in your area that cover other prescription drugs.
Chemical name: Spironolactone

Brand name: Aldactone

Typical dosage: 25mg

Typical type: Tablet1

Spironolactone is a medication used to treat fluid retention, heart failure high blood pressure and high aldosterone levels. It’s available as a generic drug or as a name brand.

Spironolactone is a medication used to treat fluid retention, heart failure, high blood pressure and high aldosterone levels. Your dose of spironolactone depends on what you are treating and how well you tolerate it.

The brand name equivalent of Spironolactone is called Aldactone. Spironolactone depletes sodium and water from the body to help lower blood pressure and get rid of excess fluid.

Common side effects include diarrhea, drowsiness, dizziness, headache, upset stomach and hair loss.

How much does Spironolactone cost with Medicare?

Spironolactone coverage and costs may vary based on the specific plan you have, as well as what coverage stage you're in.

Contact your plan carrier or consult your plan formulary for more cost information.

Does Medicare cover Spironolactone?

According to GoodRx, 100% of Medicare Advantage plans and Medicare Part D plans covered Spironolactone in 2023.1

  • Medicare Advantage plans or Part D plans that cover Spironolactone include copay amounts that can range widely from one plan to another. Plan members may also be responsible for meeting a deductible before the plan’s drug coverage kicks in.

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). 89% of 2023 Medicare Advantage plans included prescription drug coverage.2

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Spironolactone. We represent carriers such as Humana, UnitedHealthcare®, Anthem Blue Cross and Blue Shield, Aetna, Cigna Healthcare, Wellcare, or Kaiser Permanente.

You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Additional information

You can take Spironolactone with or without food, but keep it consistent each time you take it.

Keep taking Spironolactone, even if you can’t feel it working.

Potassium can be elevated in the blood by Spironolactone. This can be deadly if left untreated. The risk is higher in people with diabetes, kidney disease, chronic illness and older adults.

Your doctor will monitor you closely.

Other electrolyte problems can also occur. Watch for fluid and electrolyte problems including mood changes, confusion, muscle pain, abnormal heartbeat, dizziness, passing out, seizures, fatigue or stomach upset.

Spironolactone can increase the chance of kidney problems. Signs of kidney problems include inability to pass urine, change in how much urine is passed, blood in the urine or a noticeable weight gain.

Compare plans today.

Speak with a licensed insurance agent



This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.

Written by Hayden Gharibyar, Pharm.D.

1 GoodRx. Spironolactone. Retrieved October 2023, from

2 Freed M, et al. (Nov 10, 2022). Medicare Advantage 2023 Spotlight: First Look. Kaiser Family Foundation.