Prescription Drug Coverage

Relafen (Nabumetone) Medicare Coverage

You may be able to find Medicare plan options in your area that cover Nabumetone (generic Relafen). Learn more about Relafen and find Medicare Advantage plans in your area that cover other prescription drugs.
Chemical name: Nabumetone

Brand name: Relafen

Typical dosage: 500mg

Typical type: Tablet1

Relafen is a medication used to treat arthritis. Relafen is only available as a generic drug (Nabumetone) and comes as an oral tablet.

Relafen is a non-steroidal anti-inflammatory (NSAID) medication that contains the active ingredient Nabumetone. It is used to treat signs and symptoms of osteoarthritis and rheumatoid arthritis.

Relafen has anti-inflammatory, pain relief and fever reducing properties. The Relafen brand has been discontinued in the United States, but Nabumetone is available. It is typically taken 1-2 times daily.

Common side effects include headache, stomach pain, heartburn, upset stomach, constipation, diarrhea, gas and dizziness.

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Does Medicare cover Relafen or Nabumetone?

While some Medicare plans may not cover Relafen, 98% of Medicare Advantage plans and Medicare Part D plans cover Nabumetone.1

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). Most Medicare Advantage beneficiaries (88 percent) are enrolled in MA-PDs.2

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Nabumetone.

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You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Average costs for Nabumetone with Medicare drug coverage1

Your copay and deductible costs for any prescription drug can vary depending on what coverage stage you’re in.

Deductible stage Typical copay stage
Your deductible is the amount of money you must spend on covered drugs before your Medicare drug coverage starts paying its share of costs.

In the deductible stage, you’re responsible for the full cost of your prescription drugs.

Some Medicare prescription drug plans have a $0 deductible. Medicare drug plans cannot have a deductible more than $480 in 2022.
After you meet your Part D deductible, you enter the initial coverage period.

During this phase (the typical copay stage), you pay a copayment (flat fee) or coinsurance (percentage) for your covered medications.
$2 – $57 Free – $57

Additional information

Take your Nabumetone dose (or doses) with a full glass of water.

Nabumetone can increase your risk of heart attack or stroke. This risk may be higher in people who already have heart disease or if you have risks for heart disease. These events can happen within the first few weeks of starting Nabumetone and the risk may be higher with higher doses or with long-term use.

Avoid using Nabumetone right before or after heart bypass surgery

Negative stomach or bowel side effects can happen while taking Nabumetone. The risk is higher in older adults who take it and in people who have had stomach or bowel ulcers or bleeding before.

Other problems that can happen while taking Nabumetone include kidney problems, bleeding issues, high potassium and skin problems.

Let your doctor know if you notice any unusual symptoms while taking Nabumetone.



This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.


Written by Hayden Gharibyar, Pharm.D.