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Prescription Drug Coverage

Orencia® Medicare Coverage

You may be able to find Medicare plan options in your area that cover Orencia. Learn more about Orencia and find Medicare Advantage plans in your area that cover prescription drugs.
Chemical name: Abatacept

Typical dosage: 125mg/ml

Typical type: Injection1

Orencia® is a medication typically used to treat juvenile arthritis, psoriatic arthritis and rheumatoid arthritis. It is brand name only and is available as an intravenous or subcutaneous injection.

Orencia is a prescription medication that contains the active ingredient Abatacept. Orencia is given every 1 to 2 weeks either by IV or subcutaneous injection.

Orencia binds to immune cells to suppress the immune system and modify the process of inflammation. Orencia also reduces the presence of other inflammatory substances.

The major side effects you may see with Orencia include headache, signs of a common cold, nose and throat irritation, nausea, diarrhea, dizziness, stomach and back pain and irritation where the medication is injected.

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Does Medicare cover Orencia?

Yes! 57% of Medicare Advantage plans and Medicare Part D plans cover Orencia.1

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). Most Medicare Advantage beneficiaries (88 percent) are enrolled in MA-PDs.2

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Orencia.

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You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Average costs for Orencia with Medicare drug coverage1

Your copay and deductible costs for any prescription drug can vary depending on what coverage stage you’re in.

Deductible stage Typical copay stage
Your deductible is the amount of money you must spend on covered drugs before your Medicare drug coverage starts paying its share of costs.

In the deductible stage, you’re responsible for the full cost of your prescription drugs.

Some Medicare prescription drug plans have a $0 deductible. Medicare drug plans cannot have a deductible more than $480 in 2022.
After you meet your Part D deductible, you enter the initial coverage period.

During this phase (the typical copay stage), you pay a copayment (flat fee) or coinsurance (percentage) for your covered medications.
$1,109 – $5,036 $1,037 – $5,036

Additional information

Serious infections have happened to patients taking Orencia, particularly in patients receiving other immunosuppressive therapy.

Monitor for signs and symptoms of infection such as fever, chills, sore throat, cough, more sputum or change in sputum color, pain with passing urine, mouth sores, or a wound that will not heal. Wash hands often and stay away from people who are sick.

Orencia may worsen the conditions of patients who have Hepatitis A, Hepatitis B or COPD. Orencia may also increase the risk of certain types of cancer because of the immunosuppressive effects. Talk with your doctor about Orencia’s risks and benefits.

Orencia is not recommended for women who are pregnant or breastfeeding. Patients who are pregnant or breastfeeding should use an alternative, safer medication to treat their condition unless no other pregnancy-compatible medication is able to control disease.



This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.


Written by Hayden Gharibyar, Pharm.D.