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Prescription Drug Coverage

Nystatin (Mycostatin) Medicare Coverage

You may be able to find Medicare plan options in your area that cover Nystatin or Mycostatin. Learn more about Nystatin and find Medicare Advantage plans in your area that cover other prescription drugs.
Chemical name: Nystatin

Brand name: Mycostatin, Nystop and Nyamyc

Typical dosage: 30g of 100,000 units/g

Typical type: Topical cream1

Nystatin is a medication used to treat a variety of fungal infections. It is available as a brand name or a generic drug, and it comes as an oral capsule, oral tablet, oral liquid and as a topical cream and ointment.

Nystatin is a medication used to treat many different fungal infections including infections of the mouth, intestines and skin. Nystatin is typically used 3-4 times a day.

Nystatin kills fungal cells in the body, allowing your infection to heal. Brand name equivalents of Nystatin include Mycostatin, Nystop and Nyamyc.

Common side effects of Nystatin when taken orally include stomach pain, upset stomach and diarrhea. Topical forms of nystatin are typically well tolerated.

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Does Medicare cover Nystatin or Mycostatin?

Yes! 100% of Medicare Advantage plans and Medicare Part D plans cover Nystatin.1

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). Most Medicare Advantage beneficiaries (88 percent) are enrolled in MA-PDs.2

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Nystatin.

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You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Average costs for Nystatin with Medicare drug coverage1

Your copay and deductible costs for any prescription drug can vary depending on what coverage stage you’re in.

Deductible stage Typical copay stage
Your deductible is the amount of money you must spend on covered drugs before your Medicare drug coverage starts paying its share of costs.

In the deductible stage, you’re responsible for the full cost of your prescription drugs.

Some Medicare prescription drug plans have a $0 deductible. Medicare drug plans cannot have a deductible more than $480 in 2022.
After you meet your Part D deductible, you enter the initial coverage period.

During this phase (the typical copay stage), you pay a copayment (flat fee) or coinsurance (percentage) for your covered medications.
Free – $21 Free – $20

Additional information

If you are using the oral liquid for an oral infection, you should swish the liquid in your mouth and hold it in your mouth for several minutes before swallowing.

Use the topical form of Nystatin on your skin only and do not take it by mouth. Clean your skin before use, and wash your hands before and after.

The topical creams and ointments are typically well tolerated, but if you experience a rash or skin irritation, let your doctor know.

Use this medication as your doctor instructed, even if you begin to feel better.



This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.


Written by Hayden Gharibyar, Pharm.D.