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Prescription Drug Coverage

Mupirocin (Bactroban) Medicare Coverage

You may be able to find Medicare plan options in your area that cover Mupirocin or Bactroban. Learn more about Mupirocin and find Medicare Advantage plans in your area that cover other prescription drugs.
Chemical name: Mupirocin

Brand name: Bactroban

Typical dosage: 22g of 2%

Typical type: Topical cream1

Mupirocin is a medication used to treat skin infections, especially of the skin and nose. Mupirocin is available as a brand name or generic and comes as a topical cream or ointment.

Mupirocin is an antibiotic topical medication used to treat infections that happen on the skin or in the nose, including topical staph infections. The brand name equivalent of Mupirocin is called Bactroban.

Mupirocin is usually applied to the skin multiple times daily for up to 10 days to treat the infection. This medication blocks bacteria from forming, which allows the infection to heal.

Major side effects of Mupirocin include burning, itching and stinging of the skin where it is applied. The nasal ointment side effects include headache, stuffy nose, sore throat, cough, changes in taste and a runny nose.

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Does Medicare cover Mupirocin or Bactroban?

Yes! 100% of Medicare Advantage plans and Medicare Part D plans cover Mupirocin.1

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). Most Medicare Advantage beneficiaries (88 percent) are enrolled in MA-PDs.2

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Mupirocin.

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You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Average costs for Mupirocin with Medicare drug coverage1

Your copay and deductible costs for any prescription drug can vary depending on what coverage stage you’re in.

Deductible stage Typical copay stage
Your deductible is the amount of money you must spend on covered drugs before your Medicare drug coverage starts paying its share of costs.

In the deductible stage, you’re responsible for the full cost of your prescription drugs.

Some Medicare prescription drug plans have a $0 deductible. Medicare drug plans cannot have a deductible more than $480 in 2022.
After you meet your Part D deductible, you enter the initial coverage period.

During this phase (the typical copay stage), you pay a copayment (flat fee) or coinsurance (percentage) for your covered medications.
$2 – $16 Free – $20

Additional information

Use Mupirocin on the skin as your doctor has instructed, even if it looks like your infection is getting better. Do not use this drug orally and avoid getting it in your eyes and mouth. Wash your hands before and after use.

If you are using the single-use nose ointment, use half of the ointment from the tube into one nostril and the other half of the ointment into the other nostril. Press on your nostrils at the same time and repeat to spread the ointment into the nose.

Throw away the tube after using. Do not reuse.



This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.


Written by Hayden Gharibyar, Pharm.D.