Prescription Drug Coverage

Mucomyst (Acetylcysteine) Medicare Coverage

You may be able to find Medicare plan options in your area that cover Mucomyst or Acetylcysteine. Learn more about Mucomyst and find Medicare Advantage plans in your area that cover other prescription drugs.
Chemical name: Acetylcysteine

Brand name: Mucomyst

Typical dosage: 30ml of 20% solution

Typical type: Nebulizer solution1

Mucomyst is used to treat congestion from mucous. Mucomyst is available as a brand name or as a generic equivalent and comes as an inhaled medication.

Mucomyst is a medication that contains the active ingredient acetylcysteine. Mucomyst is used to help loosen and clear mucous in the nasal passages, sinuses and lungs.

Mucomyst is an inhaled medication. It works by dissolving the bonds in mucous that make it thick, which helps it become thin and drain more easily.

Common side effects include upset stomach, vomitting, runny nose, fatigue, mouth irritation, clammy skin and fever.

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Does Medicare cover Mucomyst or Acetylcysteine?

Yes! 100% of Medicare Advantage plans and Medicare Part D plans cover Mucomyst.1

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). Most Medicare Advantage beneficiaries (88 percent) are enrolled in MA-PDs.2

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Mucomyst.

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You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Average costs for Mucomyst with Medicare drug coverage1

Your copay and deductible costs for any prescription drug can vary depending on what coverage stage you’re in.

Deductible stage Typical copay stage
Your deductible is the amount of money you must spend on covered drugs before your Medicare drug coverage starts paying its share of costs.

In the deductible stage, you’re responsible for the full cost of your prescription drugs.

Some Medicare prescription drug plans have a $0 deductible. Medicare drug plans cannot have a deductible more than $480 in 2022.
After you meet your Part D deductible, you enter the initial coverage period.

During this phase (the typical copay stage), you pay a copayment (flat fee) or coinsurance (percentage) for your covered medications.
$5 – $187 $3 – $78

Additional information

Mucomyst is an inhaled liquid. It should only be used by breathing in through the mouth.

If you use a mask to help you inhale Mucomyst, your face may feel sticky after your dose. Wash your face with water.

Try to cough up your loosened mucus after using Mucomyst. Store Mucomyst in the refrigerator.



This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.


Written by Hayden Gharibyar, Pharm.D.