Prescription Drug Coverage

Mistral Medicare Coverage

You may be able to find Medicare plan options in your area that cover ethinyl-estradiol-norethindrone or ethinyl estradiol/levonorgestrel, generic forms of Mistral. Learn more about Mistral and find Medicare Advantage plans in your area that cover other prescription drugs.
Chemical name: Dienogest, Ethinyl Estradiol

Brand name: Mistral

Typical type: Tablet1

Mistral is a medication used for birth control and to treat heavy menstrual bleeding. Mistral is available as a brand name drug or generic and comes as an oral tablet.

Mistral is a medication that contains the active ingredients Dienogest and Ethinyl Estradiol. Mistral is used as birth control and can be used to prevent heavy menstrual bleeding.

The combination of hormones in Mistral stops ovulation and increases cervical mucous to prevent pregnancy. Mistral is taken once daily.

Common side effects of Mistral include acne, weight gain, headache, upset stomach, cramps, bloating, breast soreness, period changes, decreased interest in sex and skin changes.

How much does Ethinyl Estradiol cost with Medicare?

Ethinyl Estradiol coverage and costs may vary based on the specific plan you have, as well as what coverage stage you're in.

Contact your plan carrier or consult your plan formulary for more cost information.

Does Medicare cover Ethinyl Estradiol?

According to GoodRx, 95% of Medicare Advantage plans and Medicare Part D plans covered Ethinyl Estradiol Levonorgestrel and 96% of Medicare Advantage plans and Medicare Part D plans covered Ethinyl Estradiol Norethindrone, the generic forms of Mistral, in 2023.1

  • Medicare Advantage plans or Part D plans that cover Ethinyl Estradiol include copay amounts that can range widely from one plan to another. Plan members may also be responsible for meeting a deductible before the plan’s drug coverage kicks in.

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). 89% of 2023 Medicare Advantage plans included prescription drug coverage.2

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Ethinyl Estradiol. We represent carriers such as Humana, Aetna, UHC, Anthem BCBS, Wellcare, Cigna Healthcare, and Kaiser Permanente.

You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Additional information

A Mistral packet contains 28 total pills. 21 pills are active medication, while 7 are placebo. When you reach the placebo week, you will typically have your period.

Smoking cigarettes while using Mistral raises the risk of blood clots, stroke and heart attack. The chance is higher with increased age and the number of cigarettes smoked. It is strongly advised not to smoke.

If you are over 35 years old and smoke, do not use Mistral.

Try to take Mistral at the same time every day. Try to not vary the timing of doses by more than 12 hours. Do not skip doses, even if you do not have sex often.

This medication can take time to start working effectively, and you may need to use a back-up form of birth control like condoms to prevent pregnancy.

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This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.


Written by Hayden Gharibyar, Pharm.D.

1 GoodRx. Mistral. Retrieved October 2023, from

2 Freed M, et al. (Nov 10, 2022). Medicare Advantage 2023 Spotlight: First Look. Kaiser Family Foundation.