Prescription Drug Coverage

Mirtazapine (Remeron) Medicare Coverage

You may be able to find Medicare plan options in your area that cover Mirtazapine or Remeron. Learn more about Mirtazapine and find Medicare Advantage plans in your area that cover other prescription drugs.
Chemical name: Mirtazapine

Brand name: Remeron

Typical dosage: 15mg

Typical type: Tablet1

Mirtazapine is a medication used to treat depression. Mirtazapine is available as a brand name or generic and comes as an oral tablet.

Mirtazapine is a medication typically used to treat major depressive disorder. The brand name equivalent of Mirtazapine is called Remeron.

Mirtazapine is usually taken once daily. Mirtazapine increases the levels of norepinephrine and serotonin in the brain to improve symptoms of depression.

Major side effects of Mirtazapine include feeling sleepy, dizziness, constipation, dry mouth, feeling hungry, weight gain, fatigue and strange or odd dreams.

How much does Mirtazapine cost with Medicare?

Mirtazapine coverage and costs may vary based on the specific plan you have, as well as what coverage stage you're in.

Contact your plan carrier or consult your plan formulary for more cost information.

Does Medicare cover Mirtazapine?

According to GoodRx, 100% of Medicare Advantage plans and Medicare Part D plans covered Mirtazapine in 2023.1

  • Medicare Advantage plans or Part D plans that cover Mirtazapine include copay amounts that can range widely from one plan to another. Plan members may also be responsible for meeting a deductible before the plan’s drug coverage kicks in.

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). 89% of 2023 Medicare Advantage plans included prescription drug coverage.2

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Mirtazapine. We represent carriers such as Humana, UnitedHealthcare®, Anthem Blue Cross and Blue Shield, Aetna, Cigna Healthcare, Wellcare, or Kaiser Permanente.

You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Additional information

Mirtazapine can cause major drowsiness. If you experience drowsiness, you can take Mirtazapine at bedtime, so you don’t feel tired during the day. If you get an upset stomach after taking Mirtazapine, try taking it with food.

It may take time for you to feel the full effects of Mirtazapine. Do not stop taking Mirtazapine without talking to your doctor, even if you feel better. Stopping Mirtazapine abruptly can cause side effects and withdrawal symptoms.

Certain side effects can indicate serious health problems. Call your doctor if you experience agitation, balance changes, confusion, hallucinations, fever, abnormal heartbeats, muscle twitching or stiffness, seizures, upset stomach or headache.

These symptoms may be indicative of a condition called serotonin syndrome.

Also call your doctor if you experience a rash with red, swollen or blistered skin, red or irritated eyes or sores in your mouth, throat, nose or eyes. This can be indicative of a serious skin condition called Stevens-Johnson syndrome.

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This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.


Written by Hayden Gharibyar, Pharm.D.

1 GoodRx. Mirtazapine. Retrieved October 2023, from

2 Freed M, et al. (Nov 10, 2022). Medicare Advantage 2023 Spotlight: First Look. Kaiser Family Foundation.