Prescription Drug Coverage

Methylprednisolone (Medrol) Medicare Coverage

You may be able to find Medicare plan options in your area that cover Methylprednisolone or Medrol. Learn more about Methylprednisolone and find Medicare Advantage plans in your area that cover prescription drugs.
Chemical name: Methylprednisolone

Brand name: Medrol

Typical dosage: 4mg

Typical type: Tablet1

Methylprednisolone is a steroid medication used to treat many different diseases and inflammation. It is available as a generic or as a brand name medication and comes as an injection, liquid or oral tablet.

Methylprednisolone is a steroid medication used to control allergic reactions and to treat skin diseases, hormone disorders, eye disorders, stomach disorders, and more. It is also used to treat inflammation of the skin, joints and organs.

Your dose of Methylprednisolone will depend on what you are using it for.

Methylprednisolone is a corticosteroid that decreases inflammation, suppresses the immune system and can help control nausea in some situations. The brand name equivalent of Methylprednisolone is called Medrol.

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The most common side effects of Methylprednisolone include upset stomach, vomiting, insomnia, restlessness, sweating, dizziness and headache.

Does Medicare cover Methylprednisolone or Medrol?

Yes! 100% of Medicare Advantage plans and Medicare Part D plans cover Methylprednisolone.1

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). Most Medicare Advantage beneficiaries (88 percent) are enrolled in MA-PDs.2

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Methylprednisolone.

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You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Average costs for Methylprednisolone with Medicare drug coverage1

Your copay and deductible costs for any prescription drug can vary depending on what coverage stage you’re in.

Deductible stage Typical copay stage
Your deductible is the amount of money you must spend on covered drugs before your Medicare drug coverage starts paying its share of costs.

In the deductible stage, you’re responsible for the full cost of your prescription drugs.

Some Medicare prescription drug plans have a $0 deductible. Medicare drug plans cannot have a deductible more than $480 in 2022.
After you meet your Part D deductible, you enter the initial coverage period.

During this phase (the typical copay stage), you pay a copayment (flat fee) or coinsurance (percentage) for your covered medications.
$2 – $631 Free – $585

Additional information

For the most benefit, and to reduce side effects, take Methylprednisolone with food or a glass of milk.

If you are taking Methylprednisolone once a day, take it in the morning to avoid insomnia.

Take this medication as directed by your doctor, even if you begin to feel better. Do not stop taking Methylprednisolone without talking to your doctor first. If you have used Methylprednisolone for a long period of time, your doctor may slowly take you off of it over time.

This drug may increase your chance for getting an infection. Wash your hands often and avoid people who are sick. Call your doctor if you have any new signs of infection including fever, chills, flu-like symptoms, cough or a wound that will not heal.



This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.


Written by Hayden Gharibyar, Pharm.D.