Prescription Drug Coverage

Losartan-Hydrochlorothiazide (Hyzaar) Medicare Coverage

You may be able to find Medicare plan options in your area that cover Losartan-HCTZ. Learn more about Losartan-HCTZ and find Medicare Advantage plans in your area that cover prescription drugs.
Chemical name: Losartan-Hydrochlorothiazide

Brand name: Hyzaar

Typical dosage: 100mg/25mg

Typical type: Tablet1

Losartan-hydrochlorothiazide is used to treat high blood pressure. It is available as brand or generic and comes as an oral tablet.

Losartan-hydrochlorothiazide (Losartan-HCTZ) is a combination medication for the treatment of high blood pressure. The brand name equivalent of Losartan-HCTZ is called Hyzaar.

Losartan relaxes the blood vessels in your body, and hydrochlorothiazide (HCTZ) reduces the sodium in your body to help lower blood pressure.

You usually take Losartan-HCTZ once daily. Common side effects include dizziness, signs of a common cold, stuffy nose and back pain.

How much does Losartan/HCTZ cost with Medicare?

Losartan/HCTZ coverage and costs may vary based on the specific plan you have, as well as what coverage stage you're in.

Contact your plan carrier or consult your plan formulary for more cost information.

Does Medicare cover Losartan/HCTZ?

According to GoodRx, 100% of Medicare Advantage plans and Medicare Part D plans covered Losartan/HCTZ in 2023.1

  • Medicare Advantage plans or Part D plans that cover Losartan/HCTZ include copay amounts that can range widely from one plan to another. Plan members may also be responsible for meeting a deductible before the plan’s drug coverage kicks in.

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). 89% of 2024 Medicare Advantage plans include prescription drug coverage.2

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Losartan/HCTZ. We represent carriers such as Humana, UnitedHealthcare®, Anthem Blue Cross and Blue Shield, Aetna, Cigna Healthcare, Wellcare, or Kaiser Permanente.

You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Additional information

When you take Losartan-HCTZ, you probably won’t be able to immediately feel the benefits from this medication.

Losartan-HCTZ helps lower your blood pressure, which reduces your risk of heart attack and stroke. Keep taking your Losartan-HCTZ for the most benefit, unless your doctor tells you otherwise.

The losartan component of this medication can cause a dry cough that happens within a few months of treatment. Talk to your doctor if this becomes intolerable.

Losartan-HCTZ can cause birth defects or loss of the unborn baby.  Talk to your doctor if you are pregnant or are planning on getting pregnant.

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This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.


Written by Hayden Gharibyar, Pharm.D.

1 GoodRx. Losartan/HCTZ. Retrieved November 2023, from

2 Freed M, et al. (Nov 15, 2023). Medicare Advantage 2024 Spotlight: First Look. Kaiser Family Foundation.