Your Medicare Advantage plan comparison is just one step away!

Cartoon laptop


Compare Medicare Advantage plans and benefits in your local area.

Compare plans
Cartoon mobile phone with speech bubble.

On the phone

Our licensed insurance agents can help you compare plans and keep your current doctor.

TTY 711

Prescription Drug Coverage

Lisinopril-Hydrochlorothiazide (Zestoretic) Medicare Coverage

You may be able to find Medicare plan options in your area that cover Lisinopril-Hydrochlorothiazide (HCTZ) or Zestoretic. Learn more about Lisinopril-HCTZ and find Medicare Advantage plans in your area that cover other prescription drugs.
Chemical name: Lisinopril-Hydrochlorothiazide (HCTZ)

Brand name: Zestoretic, Prinzide

Typical dosage: 20mg/12.5mg

Typical type: Tablet1

Lisinopril-hydrochlorothiazide (HCTZ) is a medication used to treat high blood pressure. Lisinopril-HCTZ is available as a brand name drug or a generic and is an oral tablet.

Lisinopril-hydrochlorothiazide (HCTZ) is a combination of 2 medications used to treat high blood pressure. Lisinopril helps your blood vessels relax while hydrochlorothiazide helps you get rid of sodium to help lower your blood pressure.

The brand name equivalents of Lisinopril-HCTZ include Zestoretic and Prinzide.

This medication is typically taken once daily. The most common side effects of Lisinopril-HCTZ include headache, cough, fatigue and dizziness.

Find a $0 premium Medicare Advantage plan today.

Speak with a licensed insurance agent


Does Medicare cover Lisinopril-HCTZ or Zestoretic?

Yes! 100% of Medicare Advantage plans and Medicare Part D plans cover Lisinopril-hydrochlorothiazide.1

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). Most Medicare Advantage beneficiaries (88 percent) are enrolled in MA-PDs.2

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Lisinopril-hydrochlorothiazide.

Find Medicare Advantage plans with drug coverage

Compare Plans

Or call TTY Users: 711 24/7 to speak with a licensed insurance agent.


You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Average costs for Lisinopril-HCTZ with Medicare drug coverage1

Your copay and deductible costs for any prescription drug can vary depending on what coverage stage you’re in.

Deductible stage Typical copay stage
Your deductible is the amount of money you must spend on covered drugs before your Medicare drug coverage starts paying its share of costs.

In the deductible stage, you’re responsible for the full cost of your prescription drugs.

Some Medicare prescription drug plans have a $0 deductible. Medicare drug plans cannot have a deductible more than $480 in 2022.
After you meet your Part D deductible, you enter the initial coverage period.

During this phase (the typical copay stage), you pay a copayment (flat fee) or coinsurance (percentage) for your covered medications.
Free – $9 Free – $9

Additional information

Lisinopril-hydrochlorothiazide works to lower your blood pressure, lower your risk of stroke and reduce your risk of heart attack. You won’t be able to immediately feel these benefits of the drug, but you should not stop taking this medication without talking to your doctor.

The lisinopril component of this medication can cause a dry cough that happens within a few months of treatment. Talk to your doctor if this becomes intolerable. The dry cough goes away once treatment is stopped.

Low blood pressure can cause dizziness. If you have severe dizziness or you pass out, talk to your doctor.

Talk to your doctor if you cannot pass urine, you have dark urine, you are extremely tired, you have a loss of appetite or if you have yellow tinted skin or eyes, as it may be indicative of kidney or liver problems.

Do not take this medication if you are pregnant.



This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.


Written by Hayden Gharibyar, Pharm.D.