Prescription Drug Coverage

Ketoconazole (Nizoral/Extina) Medicare Coverage

You may be able to find Medicare plan options in your area that cover Ketoconazole, Nizoral or Extina. Learn more about Ketoconazole and find Medicare Advantage plans in your area that cover other prescription drugs.
Chemical name: Ketoconazole

Brand name: Extina, Nizoral

Typical dosage: 60g of 2%

Typical type: Topical cream1

Ketoconazole is a medication used to treat fungal infections. Ketoconazole is available as a brand name or generic. It comes as a topical gel or cream and as an oral tablet.

Ketoconazole is an antifungal medication used to treat a variety of fungal infections. The brand name equivalents of Ketoconazole include Extina and Nizoral.

Depending on the type of fungal infection you have, Ketoconazole can be taken by mouth or can be applied to the skin. Ketoconazole kills fungal cells and prevents new ones from forming, which allows your infection to heal.

Common side effects of the topical formulation include irritation where you use the drug. Common side effects of the oral tablet include upset stomach, diarrhea and headache.

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Does Medicare cover Ketoconazole or Nizoral?

Yes! 100% of Medicare Advantage plans and Medicare Part D plans cover Ketoconazole.1

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). Most Medicare Advantage beneficiaries (88 percent) are enrolled in MA-PDs.2

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Ketoconazole.

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You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Average costs for Ketoconazole with Medicare drug coverage1

Your copay and deductible costs for any prescription drug can vary depending on what coverage stage you’re in.

Deductible stage Typical copay stage
Your deductible is the amount of money you must spend on covered drugs before your Medicare drug coverage starts paying its share of costs.

In the deductible stage, you’re responsible for the full cost of your prescription drugs.

Some Medicare prescription drug plans have a $0 deductible. Medicare drug plans cannot have a deductible more than $480 in 2022.
After you meet your Part D deductible, you enter the initial coverage period.

During this phase (the typical copay stage), you pay a copayment (flat fee) or coinsurance (percentage) for your covered medications.
$4– $92 Free – $66

Additional information

Take Ketoconazole as directed by your doctor, even if you feel better. Your infection may improve while using Ketoconazole before you finish the entire course.

When you use the topical form of Ketoconazole, wash your hands before and after use unless you are using the drug on your hands. Put a thin layer on your skin and rub it in gently. Do not use any bandages or other coverings unless your doctor tells you to.

If you are taking the oral tablet form of Ketoconazole, do not take antacids within 1 hour before or 2 hours after you take this medication.

The oral form of Ketoconazole can have very serious side effects and should only be used if other options are not available or appropriate.

Oral ketoconazole can lead to liver problems. Signs of liver problems include dark urine, fatigue, upset stomach, vomiting or yellow skin or eyes.



This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.


Written by Hayden Gharibyar, Pharm.D.