Prescription Drug Coverage

Imbruvica® Medicare Coverage

You may be able to find Medicare plan options in your area that cover Imbruvica. Learn more about Imbruvica and find Medicare Advantage plans in your area that cover prescription drugs.
Chemical name: Ibrutinib

Typical dosage: 140mg

Typical type: Tablet1

Imbruvica® is a medication typically used to treat mantle cell lymphoma, chronic lymphocytic leukemia, small lymphocytic lymphoma, chronic Graft-Versus-Host-Disease and Waldenström macroglobulinemia. Imbruvica is brand name only and is available as an oral tablet and capsule.

Imbruvica is a prescription medication that contains the active ingredient Ibrutinib. Imbruvica is typically taken once daily and is continued until disease progression or intolerable toxicity.

Imbruvica targets proteins in cancer cells and stops the cancer cells from growing.

The major side effects of Imbruvica include constipation, diarrhea, nausea and vomiting, headache, feeling tired or weak, lack of appetite, stomach pain, muscle or joint pain, muscle spasm, anxiety, signs of a common cold, dry eyes, trouble sleeping and dizziness.

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How much does Imbruvica cost with Medicare?

Imbruvica coverage and costs may vary based on the specific plan you have, as well as what coverage stage you're in.

Contact your plan carrier or consult your plan formulary for more cost information.

Does Medicare cover Imbruvica?

According to GoodRx, 100% of Medicare Advantage plans and Medicare Part D plans covered Imbruvica in 2023.1

  • Medicare Advantage plans or Part D plans that cover Imbruvica include copay amounts that can range widely from one plan to another. Plan members may also be responsible for meeting a deductible before the plan’s drug coverage kicks in.

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). 89% of 2023 Medicare Advantage plans included prescription drug coverage.2

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Imbruvica. We represent carriers such as Humana, UnitedHealthcare®, Anthem Blue Cross and Blue Shield, Aetna, Cigna Healthcare, Wellcare, or Kaiser Permanente.

You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Additional information

Imbruvica can be used alone or in combination with bendamustine and rituximab, or with obinutuzumab.

Constipation, diarrhea, throwing up and upset stomach are very common with this drug. Talk to your doctor about medication options that can help lower these side effects and improve your quality of life.

You may have an increased chance of getting an infection while taking Imbruvica. Wash your hands often and stay away from sick people.

Imbruvica can increase the risk of serious bleeding. Be careful to avoid injury.

Imbruvica can lead to other problems, including an increased risk of other types of cancer, tumor lysis syndrome, a brain problem called progressive multifocal leukoencephalopathy, kidney problems and liver problems. Talk to your doctor about the risks and benefits of this drug.

This drug is not safe in women who are pregnant and may cause serious harm to an unborn baby. Use birth control to prevent pregnancy while taking this drug and for 1 month after your last dose.



This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.


Written by Hayden Gharibyar, Pharm.D.

1 GoodRx. Imbruvica. Retrieved October 2023, from

2 Freed M, et al. (Nov 10, 2022). Medicare Advantage 2023 Spotlight: First Look. Kaiser Family Foundation.