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Prescription Drug Coverage

Florinef (Fludrocortisone) Medicare Coverage

You may be able to find Medicare plan options in your area that cover Fludrocortisone (generic Florinef). Learn more about Florinef and find Medicare Advantage plans in your area that cover other prescription drugs.
Chemical name: Fludrocortisone

Brand name: Florinef

Typical dosage: 0.1mg

Typical type: Tablet1

Florinef is a medication used to treat Addison’s disease and salt-losing disease. It is available as a brand name drug or as a generic and comes as an oral tablet.

Florinef is a medication that contains the active ingredient Fludrocortisone. It is a medication used to treat adrenocortical insufficiency in people with Addison’s disease or salt-losing conditions such as adrenogenital syndrome.

This medication is a very potent mineralocorticoid that encourages your body to reabsorb salt.

Florinef is usually taken once daily. Florinef is typically well tolerated but can cause some trouble sleeping and increased sweating.

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Does Medicare cover Florinef or Fludrocortisone?

While some Medicare plans may not cover Florinef, 98% of Medicare Advantage plans and Medicare Part D plans cover Fludrocortisone.1

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). Most Medicare Advantage beneficiaries (88 percent) are enrolled in MA-PDs.2

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Fludrocortisone.

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You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Average costs for Fludrocortisone with Medicare drug coverage1

Your copay and deductible costs for any prescription drug can vary depending on what coverage stage you’re in.

Deductible stage Typical copay stage
Your deductible is the amount of money you must spend on covered drugs before your Medicare drug coverage starts paying its share of costs.

In the deductible stage, you’re responsible for the full cost of your prescription drugs.

Some Medicare prescription drug plans have a $0 deductible. Medicare drug plans cannot have a deductible more than $480 in 2022.
After you meet your Part D deductible, you enter the initial coverage period.

During this phase (the typical copay stage), you pay a copayment (flat fee) or coinsurance (percentage) for your covered medications.
Free – $22 Free – $22

Additional information

If you take Florinef once a day, take your dose in the morning to avoid problems with sleeping. If you take Florinef for an extended period of time, talk to your doctor before stopping the medication, as withdrawal symptoms can happen.

You may have a higher chance of getting an infection while taking Florinef. Wash your hands regularly and avoid anyone who is sick. Let your doctor know if you experience any signs of infection like fever, chills, sore throat or cough.

Florinef can cause problems with your electrolyte levels. Signs of electrolyte problems include mood changes, confusion, muscle pain or weakness, abnormal heartbeat, seizures, loss of appetite, upset stomach and vomiting.

Long-term use of Florinef can lead to cataracts, glaucoma and/or osteoporosis.



This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.


Written by Hayden Gharibyar, Pharm.D.