Prescription Drug Coverage

Florinef (Fludrocortisone) Medicare Coverage

You may be able to find Medicare plan options in your area that cover Fludrocortisone (generic Florinef). Learn more about Florinef and find Medicare Advantage plans in your area that cover other prescription drugs.
Chemical name: Fludrocortisone

Brand name: Florinef

Typical dosage: 0.1mg

Typical type: Tablet1

Florinef is a medication used to treat Addison’s disease and salt-losing disease. It is available as a brand name drug or as a generic and comes as an oral tablet.

Florinef is a medication that contains the active ingredient Fludrocortisone. It is a medication used to treat adrenocortical insufficiency in people with Addison’s disease or salt-losing conditions such as adrenogenital syndrome.

This medication is a very potent mineralocorticoid that encourages your body to reabsorb salt.

Florinef is usually taken once daily. Florinef is typically well tolerated but can cause some trouble sleeping and increased sweating.

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How much does Fludrocortisone cost with Medicare?

Fludrocortisone coverage and costs may vary based on the specific plan you have, as well as what coverage stage you're in.

Contact your plan carrier or consult your plan formulary for more cost information.

Does Medicare cover Fludrocortisone?

According to GoodRx, 100% of Medicare Advantage plans and Medicare Part D plans covered Fludrocortisone, the generic form of Florinef, in 2023.1

  • Medicare Advantage plans or Part D plans that cover Fludrocortisone include copay amounts that can range widely from one plan to another. Plan members may also be responsible for meeting a deductible before the plan’s drug coverage kicks in.

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). 89% of 2023 Medicare Advantage plans included prescription drug coverage.2

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Fludrocortisone. We represent carriers such as Humana, UnitedHealthcare®, Anthem Blue Cross and Blue Shield, Aetna, Cigna Healthcare, Wellcare, or Kaiser Permanente.

You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Additional information

If you take Florinef once a day, take your dose in the morning to avoid problems with sleeping. If you take Florinef for an extended period of time, talk to your doctor before stopping the medication, as withdrawal symptoms can happen.

You may have a higher chance of getting an infection while taking Florinef. Wash your hands regularly and avoid anyone who is sick. Let your doctor know if you experience any signs of infection like fever, chills, sore throat or cough.

Florinef can cause problems with your electrolyte levels. Signs of electrolyte problems include mood changes, confusion, muscle pain or weakness, abnormal heartbeat, seizures, loss of appetite, upset stomach and vomiting.

Long-term use of Florinef can lead to cataracts, glaucoma and/or osteoporosis.



This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.


Written by Hayden Gharibyar, Pharm.D.

1 GoodRx. Florinef. Retrieved October 2023, from

2 Freed M, et al. (Nov 10, 2022). Medicare Advantage 2023 Spotlight: First Look. Kaiser Family Foundation.