Prescription Drug Coverage

Doxycycline Hyclate (Vibramycin) Medicare Coverage

You may be able to find Medicare plan options in your area that cover Doxycycline Hyclate or Vibramycin. Learn more about Doxycycline and find Medicare Advantage plans in your area that cover prescription drugs.
Doxycycline Hyclate
Chemical name: Doxycycline Hyclate

Brand name: Acticlate, Vibramycin, Morgidox

Typical dosage: 100mg

Typical type: Capsule1

Doxycycline Hyclate is an antibiotic used to treat different types of infections and can help treat severe acne. Doxycycline is available as a brand name and as a generic drug. It typically comes as an oral capsule, but can also be an injection, liquid or tablet.

Doxycycline is an antibiotic that treats multiple infections, including urinary tract infections and dental, respiratory, skin and sexually transmitted infections, and more. It can also be used to treat acne and malaria.

The brand name equivalents of doxycycline hyclate iinclude Vibramycin, Acticlate, Morgidox, Periostat and Vibra-Tabs. Doxycycline stops the formation of bacteria in the body and kills bacteria where it already lives.

Your dose and duration of doxycycline will depend on what is being treated.

The most common side effects of doxycycline include loss of appetite, upset stomach, vomiting and diarrhea.

How much does Doxycycline Hyclate cost with Medicare?

Doxycycline Hyclate coverage and costs may vary based on the specific plan you have, as well as what coverage stage you're in.

Contact your plan carrier or consult your plan formulary for more cost information.

Does Medicare cover Doxycycline Hyclate?

According to GoodRx, 98% of Medicare Advantage plans and Medicare Part D plans covered Doxycycline Hyclate in 2023.1

  • Medicare Advantage plans or Part D plans that cover Doxycycline Hyclate include copay amounts that can range widely from one plan to another. Plan members may also be responsible for meeting a deductible before the plan’s drug coverage kicks in.

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). 89% of 2024 Medicare Advantage plans include prescription drug coverage.2

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Doxycycline Hyclate. We represent carriers such as Humana, UnitedHealthcare®, Anthem Blue Cross and Blue Shield, Aetna, Cigna Healthcare, Wellcare, or Kaiser Permanente.

You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Additional information

It is very important to take your full course of antibiotics, even if you start to feel better. Stopping your antibiotics early can result in the failure to eradicate the infection completely.

Take doxycycline on an empty stomach at least 1 hour before or 2 hours after a meal and with a full glass of water, unless directed otherwise by your doctor. Sit upright or stand for at least 30 minutes after taking this medication.

Avoid taking Pepto-Bismol, calcium, iron, magnesium, zinc, multivitamins with minerals or antacids within 2 hours of this medication.

Talk to your doctor if you have any severe side effects, especially if you experience severe diarrhea, as it may be indicative of a more serious condition.

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This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.

Written by Hayden Gharibyar, Pharm.D.

1 GoodRx. Doxycycline Hyclate. Retrieved November 2023, from

2 Freed M, et al. (Nov 15, 2023). Medicare Advantage 2024 Spotlight: First Look. Kaiser Family Foundation.