Prescription Drug Coverage

Cyclobenzaprine (Flexeril) Medicare Coverage

You may be able to find Medicare plan options in your area that cover Cyclobenzaprine or Flexeril. Learn more about Cyclobenzaprine and find Medicare Advantage plans in your area that cover other prescription drugs.
Chemical name: Cyclobenzaprine

Brand name: Flexeril

Typical dosage: 10mg

Typical type: Tablet1

Cyclobenzaprine is a medication used to treat muscle spasms. Cyclobenzaprine is available as a brand name or a generic and comes as an oral tablet or an oral capsule.

Cyclobenzaprine is a muscle relaxant medication used to treat muscle spasms. Cyclobenzaprine is usually given 1 to 3 times daily and should not be used longer than 2 to 3 weeks.

This medication works in the muscles to help relax tension and relieve symptoms. The brand name equivalent of Cyclobenzaprine is called Flexeril.

Major side effects of Cyclobenzaprine include feeling dizzy, sleepy, tired or weak, as well as dry mouth, constipation and upset stomach.

How much does Cyclobenzaprine cost with Medicare?

Cyclobenzaprine coverage and costs may vary based on the specific plan you have, as well as what coverage stage you're in.

Contact your plan carrier or consult your plan formulary for more cost information.

Does Medicare cover Cyclobenzaprine?

According to GoodRx, 100% of Medicare Advantage plans and Medicare Part D plans covered Cyclobenzaprine in 2023.1

  • Medicare Advantage plans or Part D plans that cover Cyclobenzaprine include copay amounts that can range widely from one plan to another. Plan members may also be responsible for meeting a deductible before the plan’s drug coverage kicks in.

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). 89% of 2024 Medicare Advantage plans include prescription drug coverage.2

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Cyclobenzaprine. We represent carriers such as Humana, UnitedHealthcare®, Anthem Blue Cross and Blue Shield, Aetna, Cigna Healthcare, Wellcare, or Kaiser Permanente.

You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Additional information

Cyclobenzaprine should be used in combination with rest and physical therapy for short-term relief of muscle spasm. Do not take this medication longer than your doctor tells you to.

If you are over 65 you may be at a higher risk of experiencing side effects with Cyclobenzaprine.

Cyclobenzaprine can make you very sleepy and tired. Be careful driving or doing other activities that require your full attention.

A bad condition called serotonin syndrome can happen if you take this drug with other drugs used to treat anxiety, depression, migraines and  certain other medications.

Talk to your doctor if you have a change in balance, confusion, abnormal heartbeat, muscle twitching, shaking, upset stomach or a very bad headache.

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This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.

Written by Hayden Gharibyar, Pharm.D.

1 GoodRx. Cyclobenzaprine. Retrieved November 2023, from

2 Freed M, et al. (Nov 15, 2023). Medicare Advantage 2024 Spotlight: First Look. Kaiser Family Foundation.