Prescription Drug Coverage

Azithromycin (Zithromax) Medicare Coverage

You may be able to find Medicare plan options in your area that cover Azithromycin or Zithromax. Learn more about Azithromycin and find Medicare Advantage plans in your area that cover prescription drugs.
Chemical name: Azithromycin

Brand name: Zithromax

Typical dosage: 250mg

Typical type: Tablet1

Azithromycin is an antibiotic medication used to treat infections. It is available as brand or generic and is an oral tablet or a liquid.

Azithromycin is a medication typically used to treat infections including ear infections, skin infections, streptococcus, bladder infections and others. It can also be used to help treat COPD exacerbations.

Azithromycin is an antibiotic that inhibits bacteria from replicating in your body, allowing the infection to clear. The dose of azithromycin depends on the type of infection you have.

The most common side effects of azithromycin include headache, stomach pain, diarrhea, vomitting and upset stomach.

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Does Medicare cover Azithromycin or Zithromax?

Yes! 96% of Medicare Advantage plans and Medicare Part D plans cover Azithromycin.1

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). Most Medicare Advantage beneficiaries (88 percent) are enrolled in MA-PDs.2

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Azithromycin.

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You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Average costs for Azithromycin with Medicare drug coverage1

Your copay and deductible costs for any prescription drug can vary depending on what coverage stage you’re in.

Deductible stage Typical copay stage
Your deductible is the amount of money you must spend on covered drugs before your Medicare drug coverage starts paying its share of costs.

In the deductible stage, you’re responsible for the full cost of your prescription drugs.

Some Medicare prescription drug plans have a $0 deductible. Medicare drug plans cannot have a deductible more than $480 in 2022.
After you meet your Part D deductible, you enter the initial coverage period.

During this phase (the typical copay stage), you pay a copayment (flat fee) or coinsurance (percentage) for your covered medications.
$2 – $18 Free – $18

Additional information

It is very important to take your antibiotics as directed. Even if you start to feel better, you should always finish your entire course of antibiotics as you were told by your doctor. If you stop taking your antibiotics early, there is a risk of the infection coming back.

Azithromycin can be taken with or without food. If you are taking liquid azithromycin, shake it well before you use it, so it is properly mixed.

You should not take azithromycin with antacids that have magnesium or aluminum.

Talk to your doctor if you have any severe side effects. Especially if you experience severe diarrhea, as it may indicate a more serious condition.

People often have allergic reactions to antibiotics. Tell your doctor if you experience signs of an allergic reaction such as rash, hives, wheezing, tightness in the chest or throat, or swelling of the mouth, face, lips, tongue or throat.



This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.


Written by Hayden Gharibyar, Pharm.D.