Prescription Drug Coverage

Amrix (Cyclobenzaprine ER) Medicare Coverage

If Medicare prescription drug plans in your area don’t cover Amrix (generic Cyclobenzaprine), you may be able to find plans that cover other treatments. Learn more about Amrix and find Medicare Advantage plans in your area that cover prescription drugs.
Chemical name: Cyclobenzaprine ER

Brand name: Amrix

Typical dosage: 15mg

Typical type: Capsule1

Amrix is a medication used to treat muscle spasms and muscle pain. Amrix is available as a brand name drug or as a generic and comes as an oral tablet or an oral capsule.

Amrix is a muscle relaxant medication used to treat muscle spasms and muscle pain. The generic version of Amrix is called Cyclobenzaprine ER.

Amrix is given 1 to 3 times daily and should only be used for a maximum of 2-3 weeks.

Major side effects of Amrix include dizziness, drowsiness, dry mouth, constipation and upset stomach.

How much does Amrix cost with Medicare?

Amrix coverage and costs may vary based on the specific plan you have, as well as what coverage stage you're in.

Contact your plan carrier or consult your plan formulary for more cost information.

Does Medicare cover Amrix?

According to GoodRx, Medicare Advantage plans and Medicare Part D plans don’t generally cover Amrix or Cyclobenzaprine ER in 2023.1

Medicare Advantage plans and Medicare Part D plans may cover other pain relievers and muscle relaxers.

  • Medicare Advantage plans or Part D plans that cover pain relievers or muscle relaxers include copay amounts that can range widely from one plan to another. Plan members may also be responsible for meeting a deductible before the plan’s drug coverage kicks in.

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). 89% of 2023 Medicare Advantage plans included prescription drug coverage.2

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. We represent carriers such as Humana, UnitedHealthcare®, Anthem Blue Cross and Blue Shield, Aetna, Cigna Healthcare, Wellcare, or Kaiser Permanente.

You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Additional information

Amrix can be used in combination with exercise and lifestyle modifications to help treat muscle symptoms. If you are over 65, you may be at a higher risk of experiencing side effects with Amrix.

Amrix can make you feel extremely tired. Be careful driving or doing other activities that require your full attention. Let your doctor know if you experience any odd side effects such as an abnormal or rapid heartbeat.

A condition called serotonin syndrome can happen if you take this drug with other drugs for anxiety, depression or migraines.

Talk to your doctor if you experience a change in balance, confusion, abnormal heartbeat, muscle twitching, shaking, upset stomach or a very bad headache.

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This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.


Written by Hayden Gharibyar, Pharm.D.

1 GoodRx. Amrix. Retrieved October 2023, from

2 Freed M, et al. (Nov 10, 2022). Medicare Advantage 2023 Spotlight: First Look. Kaiser Family Foundation.