Prescription Drug Coverage

Advair (Fluticasone/Salmeterol) Medicare Coverage

You may be able to find Medicare plan options in your area that cover Advair or Fluticasone/Salmeterol. Learn more about Advair and find Medicare Advantage plans in your area that cover other prescription drugs.
Chemical name: Fluticasone/Salmeterol

Brand name: Advair

Typical dosage: 250mcg/50mcg

Typical type: Inhaler1

Advair is a medication used to treat asthma and COPD. Advair comes as an aerosol inhaler which is brand name only.

Advair is a medication used to treat asthma. Advair is also used to treat chronic obstructive coronary disease (COPD) and prevent exacerbations.

Advair HFA is a typical aerosol inhaler. Advair Diskus and AirDuo RespiClick are dry powder inhalers. Your doctor will decide which inhaler type is best for you.

Advair contains two active medications: Fluticasone and Salmeterol. These medications help relax the muscles that allow you to breathe and reduces inflammation in the lungs.

Common side effects of Advair include headache, upset stomach, throat irritation and signs of a common cold.

How much does Fluticasone/Salmeterol cost with Medicare?

Fluticasone/Salmeterol coverage and costs may vary based on the specific plan you have, as well as what coverage stage you're in.

Contact your plan carrier or consult your plan formulary for more cost information.

Does Medicare cover Fluticasone/Salmeterol?

According to GoodRx, 43% of Medicare Advantage plans and Medicare Part D plans covered Fluticasone/Salmeterol, the generic form of Advair, in 2023.1

  • Medicare Advantage plans or Part D plans that cover Fluticasone/Salmeterol include copay amounts that can range widely from one plan to another. Plan members may also be responsible for meeting a deductible before the plan’s drug coverage kicks in.

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). 89% of 2023 Medicare Advantage plans included prescription drug coverage.2

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Fluticasone/Salmeterol. We represent carriers such as Humana, UnitedHealthcare®, Anthem Blue Cross and Blue Shield, Aetna, Cigna Healthcare, Wellcare, or Kaiser Permanente.

You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Additional information

If you are using any Advair product, rinse your mouth out after each inhalation. Swish water around your mouth and spit it out, do not swallow.

Advair helps control your asthma or COPD with continued use. Keep using your inhaler as instructed by your doctor, even if you feel better. Talk to your doctor before stopping Advair.

If you are using the Advair HFA aerosol inhaler, shake the inhaler well. Before you first use the inhaler, prepare it by spraying 4 test sprays into the air away from the face.

If the inhaler hasn’t been used for more than 4 weeks or if it is dropped, spray 2 times into the air to prepare it again.

If you have diabetes, Advair can increase your blood sugar. Let your doctor know if your breathing becomes worse or if you experience continued coughing after using Advair.

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This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.


Written by Hayden Gharibyar, Pharm.D.

1 GoodRx. Advair. Retrieved October 2023, from

2 Freed M, et al. (Nov 10, 2022). Medicare Advantage 2023 Spotlight: First Look. Kaiser Family Foundation.