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Prescription Drug Coverage

Regonol (Pyridostigmine) Medicare Coverage

You may be able to find Medicare plan options in your area that cover Pyridostigmine (generic Regonol). Learn more about Regonol and find Medicare Advantage plans in your area that cover other prescription drugs.
Chemical name: Pyridostigmine

Brand name: Regonol

Typical dosage: 60mg

Typical type: Tablet1

Regonol is a medication used to reverse the effects of muscle relaxants and to strengthen muscles. Regonol is available as a brand name or generic drug and comes as an injection.

Regonol is a medication that contains the active ingredient Pyridostigmine. Regonol is used to strengthen muscles and to reverse the effects of muscle relaxants after anesthesia from surgery.

Regonol is typically given in the hospital. It increases the levels of a chemical called acetylcholine in the muscles to improve muscle function.

Side effects are rare when taking Regonol, however upset stomach and muscle cramps can occur.

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Does Medicare cover Regonol or Pyridostigmine?

While some Medicare plans may not cover Regonol, some Medicare Advantage plans and Medicare Part D plans may cover generic Pyridostigmine.

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). Most Medicare Advantage beneficiaries (88 percent) are enrolled in MA-PDs.1

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Pyridostigmine.

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You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Average costs for Pyridostigmine with Medicare drug coverage

Your copay and deductible costs for any prescription drug can vary depending on what coverage stage you’re in and the Medicare drug plan you have.

Deductible stage Typical copay stage
Your deductible is the amount of money you must spend on covered drugs before your Medicare drug coverage starts paying its share of costs.

In the deductible stage, you’re responsible for the full cost of your prescription drugs.

Some Medicare prescription drug plans have a $0 deductible. Medicare drug plans cannot have a deductible more than $480 in 2022.
After you meet your Part D deductible, you enter the initial coverage period.

During this phase (the typical copay stage), you pay a copayment (flat fee) or coinsurance (percentage) for your covered medications.

Additional information

Regonol is very well tolerated in most people who take it.

Side effects that could indicate a more serious reaction include stomach cramps, vomiting, diarrhea, excess saliva, pupil constriction, sweating, muscle cramps, twitching, weakness and slowed heartbeat.

Regonol is given as an injection into a vein, usually in the hospital. You will be monitored closely after receiving the medication.



This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.


Written by Hayden Gharibyar, Pharm.D.