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Prescription Drug Coverage

Compazine (Prochlorperazine) Medicare Coverage

You may be able to find Medicare plan options in your area that cover Prochlorperazine (generic Compazine). Learn more about Compazine and find Medicare Advantage plans in your area that cover other prescription drugs.
Chemical name: Prochlorperazine

Brand name: Compazine

Typical dosage: 10mg

Typical type: Tablet1

Compazine is a used to treat nausea and vomiting. Compazine is available as a brand name or generic drug and comes in many different dosage forms.

Compazine is a medication that contains the active ingredient Prochlorperazine. Compazine is used to manage severe nausea and vomiting.

Compazine stops the release of hormones that can lead to nausea and vomiting. Compazine is available as an injection, a suppository or an oral tablet.

Common side effects include dizziness, nervousness, constipation, dry mouth and fatigue.

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Does Medicare cover Compazine or Prochlorperazine?

While some Medicare plans may not cover Compazine, some Medicare Advantage plans and Medicare Part D plans may cover generic Prochlorperazine.

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). Most Medicare Advantage beneficiaries (88 percent) are enrolled in MA-PDs.1

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Prochlorperazine.

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You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Average costs for Prochlorperazine with Medicare drug coverage

Your copay and deductible costs for any prescription drug can vary depending on what coverage stage you’re in and the Medicare drug plan you have.

Deductible stage Typical copay stage
Your deductible is the amount of money you must spend on covered drugs before your Medicare drug coverage starts paying its share of costs.

In the deductible stage, you’re responsible for the full cost of your prescription drugs.

Some Medicare prescription drug plans have a $0 deductible. Medicare drug plans cannot have a deductible more than $480 in 2022.
After you meet your Part D deductible, you enter the initial coverage period.

During this phase (the typical copay stage), you pay a copayment (flat fee) or coinsurance (percentage) for your covered medications.

Additional information

Compazine should not be used in older adults to treat mental problems related to dementia.

Muscle problems can happen while taking Compazine. It can become less severe after stopping Compazine but may not go away completely. This risk is greater with higher doses, longer use, in women and in people with diabetes.

Let your doctor know if you experience muscle pain or if you cannot control your body movements.

If you use the suppository, wash your hands before and after use. If the suppository has become soft, put it in the refrigerator or run cold water over it before application.



This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.


Written by Hayden Gharibyar, Pharm.D.