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Prescription Drug Coverage

Amantadine (Symadine/Symmetrel) Medicare Coverage

You may be able to find Medicare plan options in your area that cover Amantadine (generic Symadine or Symmetrel). Learn more about Amantadine and find Medicare Advantage plans in your area that cover other prescription drugs.
Chemical name: Amantadine

Brand name: Symadine, Symmetrel

Typical dosage: 100mg

Typical type: Tablet1

Amantadine is a medication used to treat or prevent the flu, treat Parkinson’s disease and to treat side effects of other medications. Amantadine is available as a brand name or generic drug and comes as an oral capsule, oral syrup and an oral tablet.

Amantadine is a medication used to treat or prevent the flu. It can also be used to treat Parkinson’s disease and is used to treat extrapyramidal side effects of some other drugs including muscle spasms, restless muscles, slowed movement, tremors and more.

The brand name equivalents of Amantadine include Symadine and Symmetrel.

Amantadine has anti-virus effects and can help improve muscle symptoms of Parkinson’s disease. It is typically taken 1-2 times daily, depending on what form of the medication you take.

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Common side effects of Amantadine include upset stomach, insomnia, fatigue, headache, dry mouth, diarrhea, constipation, anxiety and dry nose.

Does Medicare cover Amantadine or Symadine/Symmetrel?

Some Medicare Advantage plans and Medicare Part D plans may cover generic Amantadine.

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). Most Medicare Advantage beneficiaries (88 percent) are enrolled in MA-PDs.1

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Amantadine.

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You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Average costs for Amantadine with Medicare drug coverage

Your copay and deductible costs for any prescription drug can vary depending on what coverage stage you’re in and the Medicare drug plan you have.

Deductible stage Typical copay stage
Your deductible is the amount of money you must spend on covered drugs before your Medicare drug coverage starts paying its share of costs.

In the deductible stage, you’re responsible for the full cost of your prescription drugs.

Some Medicare prescription drug plans have a $0 deductible. Medicare drug plans cannot have a deductible more than $480 in 2022.
After you meet your Part D deductible, you enter the initial coverage period.

During this phase (the typical copay stage), you pay a copayment (flat fee) or coinsurance (percentage) for your covered medications.

Additional information

If you take the extended-release tablet form of Amantadine, take in the morning. If you take the extended-release capsules, take your dose at bedtime if taking once a day.

You may need to avoid drinking alcohol with some Amantadine products.

Amantadine can make you extremely tired. Be careful when driving or doing other important activities, as some people have fallen asleep during these activities.

Overdoses can happen with Amantadine. Be careful not to take more than your doctor instructs you to.



This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.


Written by Hayden Gharibyar, Pharm.D.