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Prescription Drug Coverage

Rifampin (Rifadin) Medicare Coverage

You may be able to find Medicare plan options in your area that cover Rifampin (Rifadin). Learn more about Rifampin and find Medicare Advantage plans in your area that cover other prescription drugs.
Chemical name: Rifampin

Brand name: Rifadin

Typical dosage: 300mg

Typical type: Tablet1

Rifampin is a medication used to prevent meningitis and to treat tuberculosis. Rifampin is available as a brand name drug or as a generic and comes as an IV injection or an oral capsule.

Rifampin is an antibiotic used to treat asymptomatic carriers of the bacteria that causes meningitis, in order to eliminate the infection before it causes serious harm. It is also used to treat tuberculosis.

Rifampin stops bacteria from forming, which helps stop the infection from spreading and allows the infection to heal. Rifampin is typically taken 1-2 times daily.

The brand name equivalent of Rifampin is called Rifadin.

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Common side effects of rifampin include diarrhea, fatigue, gas, headache, upset stomach, heartburn and cramps.

Does Medicare cover Rifampin or Rifadin?

Some Medicare Advantage plans and Medicare Part D plans may cover Rifampin.

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). Most Medicare Advantage beneficiaries (88 percent) are enrolled in MA-PDs.1

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Rifampin.

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You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Average costs for Rifampin with Medicare drug coverage

Your copay and deductible costs for any prescription drug can vary depending on what coverage stage you’re in and the Medicare drug plan you have.

Deductible stage Typical copay stage
Your deductible is the amount of money you must spend on covered drugs before your Medicare drug coverage starts paying its share of costs.

In the deductible stage, you’re responsible for the full cost of your prescription drugs.

Some Medicare prescription drug plans have a $0 deductible. Medicare drug plans cannot have a deductible more than $480 in 2022.
After you meet your Part D deductible, you enter the initial coverage period.

During this phase (the typical copay stage), you pay a copayment (flat fee) or coinsurance (percentage) for your covered medications.

Additional information

Meningitis is an infection of the brain, while tuberculosis is an infection of the lungs.

Rifampin is typically used for 2 days to prevent meningitis or for multiple months (along with other medications) for the treatment of tuberculosis.

Take Rifampin on an empty stomach 1 hour before or 2 hours after any meals. Do not take any antacids within 1 hour of taking Rifampin.

The color of your body fluids (sweat, saliva, urine, etc.) may turn an orange or red color. This is normal while taking Rifampin and is not cause for concern.

Let your doctor know if you experience any kidney problems such as the inability to pass urine, blood in your urine or noticeable weight changes.



This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.


Written by Hayden Gharibyar, Pharm.D.