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Prograf (Tacrolimus) Medicare Coverage

You may be able to find Medicare plan options in your area that cover Tacrolimus (generic Prograf). Learn more about Prograf and find Medicare Advantage plans in your area that cover other prescription drugs.
Chemical name: Tacrolimus

Brand name: Prograf

Typical dosage: 1mg

Typical type: Capsule1

Prevacid is a medication used to treat disorders related to excess stomach acid. Prevacid is available as a brand name or generic drug and comes as an oral capsule or a disintegrating tablet.

Prograf is a medication that contains the active ingredient Tacrolimus. It is used to prevent rejection of transplanted organs after operations such as heart, kidney and liver transplants.

Prograf works by blocking T cell function of the immune system so that it doesn’t attack the new organ. It is typically taken twice daily, but extended-release formulations may only be taken once daily.

Common side effects of Prograf include fatigue, dizziness, headache, constipation, diarrhea, upset stomach, heartburn, insomnia, back pain and nose or throat irritation.

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Does Medicare cover Prograf or Tacrolimus?

While some Medicare plans may not cover Prograf, some Medicare Advantage plans and Medicare Part D plans in your area may cover generic Tacrolimus.

  • Medicare Advantage plans that offer prescription drug coverage are called Medicare Advantage Prescription Drug Plans (MA-PD). Most Medicare Advantage beneficiaries (88 percent) are enrolled in MA-PDs.1

  • Medicare prescription drugs plans each have their own formulary, or drug list, that details what prescription drugs are covered by the plan and how they are covered.

Drug coverage may vary based on plan availability. You may be able to find Medicare Advantage plan options in your area that cover Tacrolimus.

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You can also compare Part D prescription drug plans available where you live and enroll in a Medicare prescription drug plan online when you visit

Average costs for Tacrolimus with Medicare drug coverage

Your copay and deductible costs for any prescription drug can vary depending on what coverage stage you’re in and the Medicare drug plan you have.

Deductible stage Typical copay stage
Your deductible is the amount of money you must spend on covered drugs before your Medicare drug coverage starts paying its share of costs.

In the deductible stage, you’re responsible for the full cost of your prescription drugs.

Some Medicare prescription drug plans have a $0 deductible. Medicare drug plans cannot have a deductible more than $480 in 2022.
After you meet your Part D deductible, you enter the initial coverage period.

During this phase (the typical copay stage), you pay a copayment (flat fee) or coinsurance (percentage) for your covered medications.

Additional information

Prograf can increase your risk of getting cancer like lymphoma or skin cancer. Have your skin checked regularly and let the doctor know if you develop a new wart, skin sore, red bumps that bleed or don’t heal or a change in color or size of a mole.

Talk to the doctor if you experience a swollen gland, night sweats, shortness of breath or unintentional weight loss.

Prograf can also increase your risk of serious infections. Prograf weakens your immune system, which makes you vulnerable to infection. Signs of infection can include fever, chills, flu-like symptoms, sore throat or cough.



This article is for informational purposes only. It is not healthcare advice, treatment, or diagnosis. It is not an endorsement of or recommendation for this medication. Speak to your doctor or healthcare provider about your specific healthcare needs, including your prescription medications. Only take medication as directed by your doctor.

Coverage and costs of prescription medications will vary by Medicare plan. Not all plans are available in all areas.


Written by Hayden Gharibyar, Pharm.D.